Release notes – v1.2

Highlight of features included in current release Data editor – improved column headers and data precision Data editor – fixed a number of bugs related to the tables’ validation process Improved the search functionality Improved several error messages displayed by the software Assessment wizard – the statistics step retains previous selections when closing & reopening or […]

Read More >

Release note – v.1.1

Highlight of features included in current release New and improved filtering system to accommodate more complex filter types Infinite scrolling implemented – Users can scroll past 25+ files in each folder Improved calculation of the infants’ body-weight in the 365-day diaries created with the matched-diet model Dietary model random spreads the data from neighbour to cover n non-consecutive […]

Read More >

The REJV tool

Introduction The entire Residential Exposure Joint Venture (REJV) database is stored in the CARES NG® platform but it is available only to the REJV members This database collects, organizes and analyses label and use information for pesticide products used in and around the home; please refer to the section The REJV database for more information. The REJV […]

Read More >

Glossary

a.i. (Active Ingredient) The chemical or substance in a pesticide product intended to kill, repel, attract, mitigate or control a pest or that acts as a plant growth regulator. The other ingredients in the formulation are referred to as inerts. Absorbed Dose The amount of a substance penetrating across the absorption barriers of an organism, […]

Read More >

Release notes – v1.0

Highlight of features included in current release The non-temporal Residential model. Allowing user to manage, run and rerun exposure assessments with different combinations of products and scenarios using a user-friendly wizard to manage the all the inputs required. Dietary model, full implementation, managed by a user friendly wizard allowing a user to: run and rerun dietary […]

Read More >

Overview of user interface

This section provides a high level overview of the user interface of CARES NG. More detailed instruction can be found in the documentation. The user interface is comprised of three major components. File management system Data editor Wizard File management system The file management systems works in a similar way to the file management systems […]

Read More >

Assessment wizard overview

The assessment wizard is a step-wise interface that will guide you through the different input data and parameters required to run either a dietary or a residential exposure assessment. The assessment wizard is divided into three areas: Inputs area: it consists of the wide white area that contains the list of the input parameters and […]

Read More >

How to run a dietary assessment

Step 1 – How to set up a new dietary assessment To set up a new assessment, navigate to the folder where you wish to store it, click on in the top right corner and then select Assessment from the dropdown menu. The first thing to do is to assign a proper name to the […]

Read More >

How to run a water assessment

The Water Model mainly represents a special case of the Dietary Model. The NHANES database contains the consumption data of three water types, namely: Water, direct, tap Water, direct, bottled Water, indirect, all sources The three water types are listed in the Food table, as shown below. They differentiate from the other foods listed in […]

Read More >

How to create a new assessment

It is possible to run an assessment from any folder of CARES NG® with the only exception of the CARES Data folder. This is a read-only folder which contains the databases that are required to run an exposure assessment; please refer to the section The Databases of this manual for more information. Go into the […]

Read More >

How to run a cumulative assessment

Step 1 – How to set up a new cumulative assessment To set up a new assessment, navigate to the folder where you wish to store it, click on in the top right corner and then select Assessment from the dropdown menu. The first thing to do is to assign a name to the assessment. […]

Read More >

Run a residential assessment

Step 1 – Starting a new assessment It is possible to run an assessment from any folder in CARES NG®, apart from the folder CARES Data which is read-only. Go into the folder where you want to store your assessment Choose Create > Assessment You can now assign a name to your assessment. For this […]

Read More >

Output

To view an assessment output click on within the Notifications area in the top right corner, or on the assessment file. Dietary assessment The dietary assessment output consists of the following tables displayed as tabs, similar to Excel spreadsheets: Results – it contains the list of the summary statistics calculated over the exposure levels for […]

Read More >

Run a dietary assessment

Step 1 – Starting a new assessment It is possible to run an assessment from any folder in CARES NG®, apart from the folder CARES Data which is read only. Go into the folder where you want to store your assessment Choose Create > Assessment You can now assign a name to your assessment. For […]

Read More >

Statistics

This page contains the list of check-boxes included in the Statistics step of the assessment wizard; these check-boxes give you the capability to customize the output of the dietary and residential assessments. The list changes according to the options selected in the previous steps of the wizard. In particular, it depends on the type of […]

Read More >

Cumulative Risk Characterization

Cumulative exposure is defined as the exposure to multiple chemicals from multiple pathways acting through a common mechanism of toxicity. The first step in performing a cumulative risk assessment is to identify a common mechanism group. This involves identifying pesticides that share a common mode of action. Once a group of pesticides with a common […]

Read More >

Aggregate Risk Characterization

Aggregate risk assessments allow for the evaluation of potential adverse health effects that could occur as a result of exposure to a single chemical from all routes (oral, dermal, inhalation) and sources (dietary, water, residential) of exposure combined. Any appropriate benchmark of toxicity (Point of Departure) selected by the risk assessor such as the no […]

Read More >

Fraction Crop Treated

The Fraction of Crop Treated (FCT) represents the assumption that the whole crop has been treated with the pesticide(s) under analysis. CARES NG® sets the fraction of crop treated of each raw agricultural commodity equal to 100% by default. The FCT data are stored in the column Percentage of Crop Treated of the Foods table; […]

Read More >

Processing factors

Each residue value included in the final distribution that will be used in the acute, multi-day and within-day assessments in the Food Model will be multiplied times the processing factor PFk related to the k-th raw agricultural commodity (RAC) under analysis: Residuej,k = Residuej,k * PFk for each pesticide j=1,…,M and for each RAC k=1,…,K […]

Read More >

LOD rules

This section contains a detailed description of the different options for entering or selecting the residue values to be used in the food exposure assessments for acute, multi-day and within-day assessment especially as relates to measurement values below the Limit of Detection (LOD) or the Limit of Quantification (LOQ). The outputs of these options will […]

Read More >